COVID-19 Research Projects

Explore listed projects, find initiatives that need your support and connect with the responsible researchers.

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1 to 5 of 42
Repurposing

Bralacidin Tetrahydrochloride

Innovation is evaluating Brilacidin, under Fast Track designation, in a Phase 2 clinical trial as an oral rinse to attenuate Oral...

Research Institution

Innovation Pharmaceuticals

Current Status

Pre-Clinical

Molecule Type

Small molecule

Needs
No items found.
Vaccine

INO-4800 Cellectra

INO-4800 is a DNA vaccine candidate matched to the novel coronavirus SARS-CoV-2, which causes the COVID-19 disease in humans. Inovio's...

Research Institution

Inovio Pharmaceuticals Inc.; Beijing Advaccine Biotechnology.; US Department of Defense.; Ology Bioservices Inc.

Current Status

Phase I

Molecule Type

Nucleic acid-based

Needs
No items found.
Vaccine

TNX-1800 Vaccine

TNX-1800 (live modified horsepox virus vaccine) is being developed by Tonix Pharmaceuticals in a strategic collaboration with Southern...

Research Institution

Tonix

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Vaccine

Novavax Vaccine

Novavax, Inc. recently announced progress in its efforts to develop a novel vaccine to protect against coronavirus disease COVID-19...

Research Institution

Novavax Inc; Emergent BioSolutions Inc.

Current Status

Pre-Clinical

Molecule Type

Subunit vaccines

Needs
No items found.
Vaccine

Institut Pasteur Vaccine

CEPI, the Coalition for Epidemic Preparedness Innovations, today added an eighth COVID-19 vaccine candidate to its portfolio. CEPI will...

Research Institution

Institut Pasteur; Themis; University of Pittsburg

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Antibody

Regeneron Sarilumab Antibodies

Based on recent clinical data from studies in China with another IL-6 inhibitor, we believe there is a potential role for Kevzara®...

Research Institution

Regeneron

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Novel Therapeutic

BCX4430 Novel Therapeutic

This nucleoside RNA polymerase inhibitor disrupts the viral replication process and has the potential to fight multiple viral threats...

Research Institution

Biocryst Pharma

Current Status

Phase II

Molecule Type

Protein-based

Needs
No items found.
Novel Therapeutic

Anti-SARS-CoV-2 polyclonal hyperimmune globulin

Takeda is initiating the development of an anti-SARS-CoV-2 polyclonal hyperimmune globulin (H-IG) to treat high-risk individuals with...

Research Institution

Takeda Pharmaceutical Company

Current Status

Pre-Clinical

Molecule Type

Small molecule

Needs
No items found.
Vaccine

Vaxart Vaccine

Bay Area-based Vaxart, Inc. has obtained positive pre-clinical results for its COVID-19 vaccine candidates, with several of the vaccine...

Research Institution

Vaxart

Current Status

Pre-Clinical

Molecule Type

Subunit vaccines

Needs
No items found.
Repurposing

AT-100 Repurposing

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation...

Research Institution

Airway Therapeutics

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Novel Therapeutic

Comprehensive Coronavirus Research and Development Program

Several research groups at Columbia University Irving Medical Center and the School of Engineering and Applied Sciences have projects...

Research Institution

Columbia University

Current Status

Pre-Clinical

Molecule Type

Needs
No items found.
Antibody

Rapid Development of Human Neutralizing Monoclonal Antibodies for SARS-CoV-2

We are rapidly developing human neutralizing monoclonal antibodies for SARS-CoV-2. We need funds or services in kind for manufacture and...

Research Institution

Vanderbilt Vaccine Center

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
Funding
Partnerships
Expert Advice
Repurposing

SNG001 Repurposing

Researchers have revealed they will be trialling an inhaled drug named SNG001 in 100 COVID-19 patients to see if the interferon beta 1a...

Research Institution

Synairgen Research

Current Status

Phase II

Molecule Type

Other

Needs
No items found.
Vaccine

Novel mRNA Vaccine Method

Using a new vaccine method, certain virus genes can be injected in the form of their RNA. They then stimulate the body’s cells to produce...

Research Institution

University of Zürich

Current Status

Pre-Clinical

Molecule Type

Nucleic acid-based

Needs
No items found.
Vaccine

NIV Pune Vaccine Candidate

The Indian Council of Medical Research (ICMR) has confirmed that India will be part of the solidarity trials being conducted by the WHO...

Research Institution

National Institute of Virology-Pune

Current Status

Pre-Clinical

Molecule Type

Unknown

Needs
No items found.
Antibody

TJM2 Antibody

TJM2 is an internally discovered neutralizing antibody against human GM-CSF, an important cytokine that plays a critical role in chronic...

Research Institution

I-Mab

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Repurposing

OYA1 Antiviral

OyaGen is focused on the identification and early development of novel therapeutics for the treatment of viral diseases including HIV,...

Research Institution

OyaGen

Current Status

Pre-Clinical

Molecule Type

Small molecule

Needs
No items found.
Vaccine

Miller School gp96-based vaccine

“We plan to leverage Heat Biologics’ proprietary vaccine platform to stimulate T-cell immune responses, which play a crucial role in...

Research Institution

University of Miami Miller School of Medicine

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Vaccine

STARR Technology Coronavirus Vaccine

Arcturus Therapeutics, a leading messenger RNA medicines company, and Duke-NUS Medical School (Duke-NUS), a research intensive, graduate...

Research Institution

Duke-NUS Medical School

Current Status

Pre-Clinical

Molecule Type

Needs
No items found.
Vaccine

Rapid RNA Vaccine Development

Professor Robin Shattock and his team in Imperial College London’s Department of Infectious Disease developed a candidate vaccine within...

Research Institution

Imperial College London

Current Status

Pre-Clinical

Molecule Type

Nucleic acid-based

Needs
No items found.
Repurposing

Actemra Antiviral Repurposing

Roche has announced that the US Food and Drug Administration (FDA) has formally approved its phase 3 trial of Actemra in severely ill...

Research Institution

Roche

Current Status

Phase III

Molecule Type

Protein-based

Needs
No items found.
Vaccine

Karolinska Institute Vaccine

Researchers worldwide are trying to develop a vaccine and antiviral treatments against the new corona virus spreading in China. At...

Research Institution

Karolinska Institute

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Novel Therapeutic

TZLS-501 Novel Therapeutic

Tiziania is developing a fully human monoclonal antibody (mAb) targeting the receptor for IL-6. This asset was in-licensed from Novimmune...

Research Institution

Tiziana Life Sciences

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Vaccine

Moderna Vaccine mRNA-1273

Founded in 2010, Moderna uses messenger RNA, which carries genetic information from DNA to ribosomes to produce proteins. Moderna hijacks...

Research Institution

Moderna; National Institute of Allergy and Infectious Diseases

Current Status

Phase I

Molecule Type

Nucleic acid-based

Needs
No items found.
Vaccine

Replication-deficient Simian Adenoviral Vector Vaccine

We have developed a replication-deficient simian adenoviral vector vaccine expressing the SARS-CoV-2 surface Spike protein...

Research Institution

University of Oxford

Current Status

Pre-Clinical

Molecule Type

Subunit vaccines

Needs
Funding
Partnerships
Expert Advice
Vaccine

Novel Approach to Vaccine Development

The World Health Organization has indicated that it will be approximately 18 months before a vaccine for COVID-19 is developed. Using our...

Research Institution

University of Iowa, Carver College of Medicine

Current Status

Pre-Clinical

Molecule Type

Other

Needs
No items found.
Vaccine

VIDO-InterVac Vaccine Candidate

Canada announced $23.3 million in total support for the University of Saskatchewan's (USask) Vaccine and Infectious Disease Organization...

Research Institution

University of Saskatchewan

Current Status

Pre-Clinical

Molecule Type

Unknown

Needs
No items found.
Vaccine

BNT162 Vaccine

BNT162 is a vaccine candidate based upon mRNA. The four vaccine candidates are the first candidates from BioNTech’s COVID-19-focused...

Research Institution

Pfizer Inc; BioNTech SE

Current Status

Pre-Clinical

Molecule Type

Nucleic acid-based

Needs
No items found.
Repurposing

BPI-002 Antiviral

BeyondSpring Inc. recently announced the submission of a provisional US patent application for its pipeline asset BPI-002, for methods of...

Research Institution

BeyondSpring Inc

Current Status

Pre-Clinical

Molecule Type

Small molecule

Needs
No items found.
Medical Device

InVent Automated Emergency Ventilator (AEV) project

Our team has a prototype of a low-cost, easy-to-use ventilator that is optimized for emergency and mass casualty scenarios. The team is...

Research Institution

Duke University

Current Status

Pre-Clinical

Molecule Type

Needs
Funding
Novel Therapeutic

APN01 Novel Therapeutic

A University of British Columbia investigator led an international team that has discovered an experimental drug that effectively blocks...

Research Institution

University of British Columbia; APEIRON Biologics; University of Toronto

Current Status

Phase I

Molecule Type

Other

Needs
No items found.
AI Drug Discovery

AI-Driven Drug Discovery for COVID-19

AI company Gero has reviewed the existing drugs and other agents tested on humans and found potential coronavirus treatments. The list of...

Research Institution

Gero AI

Current Status

Pre-Clinical

Molecule Type

Needs
Funding
Vaccine

Rapid Vaccine Development Using Molecular Clamp

The University of Queensland has been asked to develop a vaccine for the recent coronavirus outbreak at unprecedented speed, using new...

Research Institution

University of Queensland

Current Status

Pre-Clinical

Molecule Type

Needs
No items found.
Repurposing

Cyclica/Institute Materia Medica Drug Repurposing Initiative

Chinese medical research institution in Beijing, Institute of Materia Medica, Chinese Academy of Medical Sciences, enters a strategic...

Research Institution

Institute Materia Medica, Chinese Academy of Medical Sciences

Current Status

Pre-Clinical

Molecule Type

Needs
No items found.
Vaccine

Avian Coronavirus Infectious Bronchitis Virus (IBV) vaccine

Scientists at MIGAL Research Institute in Israel expect to start producing a Covid-19 vaccine in the next eight-ten weeks, based on their...

Research Institution

MIGAL Research Institute

Current Status

Pre-Clinical

Molecule Type

Whole-pathogen vaccines

Needs
No items found.
Vaccine

HKU Vaccine Effort

HKU has joined a global effort to develop a vaccine candidate against COVID-19, led the Coalition for Epidemic Preparedness Innovations...

Research Institution

The University of Hong Kong

Current Status

Pre-Clinical

Molecule Type

Whole-pathogen vaccines

Needs
No items found.
Vaccine

Ad5-nCoV Vaccine

Ad5-nCoV is the first novel coronavirus vaccine for COVID-19 in a Phase 1 Clinical Trial in China. The vaccine candidate is built upon...

Research Institution

CanSinoBIO

Current Status

Phase I

Molecule Type

Gene therapies

Needs
No items found.
Repurposing

AmnioBoost Repurposing

AmnioBoost has potential for use in the treatment of ARDS, which is the principal cause of death in COVID-19 infection. Mortality in...

Research Institution

Lattice Biologics

Current Status

Phase I

Molecule Type

Other

Needs
No items found.
Vaccine

UGA Coronavirus Vaccine

A team of researchers at the University of Georgia are developing and testing new vaccines and immunotherapies to combat the novel...

Research Institution

University of Georgia

Current Status

Pre-Clinical

Molecule Type

Protein-based

Needs
No items found.
Diagnostic

End-to-End Diagnostics Solution for COVID-19: Diagnosis, Treatment Selection, and Monitoring of Disease Course

An expert team of researchers and clinicians in microbiology, virology, pathology, molecular science, and immunology at the Icahn School...

Research Institution

Icahn School of Medicine at Mount Sinai

Current Status

Pre-Clinical

Molecule Type

Other

Needs
No items found.
Repurposing

NP-120 Ifenprodil Repurposing

Algernon is a drug re-purposing company that investigates safe, already approved drugs for new disease applications, moving them...

Research Institution

Algernon Pharmaceuticals

Current Status

Phase II

Molecule Type

Other

Needs
No items found.
Antibody

Ieronlimab Antibody

Blood samples fromdays 0, 3, and 7demonstrated that leronlimab induced significant reductions in the cytokine storm among all 7 severely...

Research Institution

CytoDyn

Current Status

Phase II

Molecule Type

Protein-based

Needs
No items found.